I think most of us North Americans living in the past 50 to 75 years assume peace and prosperity and health are the given. So we are shocked and horrified when we encounter the "variable" of violence and poverty and sickness.
Throughout human history, however, and in much of the world today, the "given" is violence and poverty and sickness. People kill each other. The rich exploit the poor. Disease runs rampant. THAT is the given. The variable is, how do we human beings respond to it, and whose side is God on when we do? -- on the side of the murderers, exploiters, and illness, or on the side of peace-makers, the poor and oppressed (and their allies) struggling to break free, and the healers?
The radical claim of Judeo-Christianity, so wonderfully encapsulated in the Magificat, is who God sides with. Who God intervenes for.